QivanaRx Glow Lab

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Probe · tadalafil · 3 min read

How long does as-needed Cialis last at 24 hours?

At 24 hours after the tablet, the mean per-patient percentage of attempts that led to intercourse was 67% on Cialis 20 mg, 56% on 10 mg, and 42% on placebo. Patients were encouraged to make four separate attempts at the assigned dose and that 24-hour timepoint. One timed program enrolled 483 men. Highlights still say up to 36 hours. This vault's as-needed start is 10 mg.

Medically reviewed by Dr. Mateo Ruiz, MD - Clinical pharmacology, Barcelona

Last reviewed

Updated

01How does the 17.5-hour half-life sit next to 24 hours?

Forest-green still life: wall clock at midnight and one tablet on a long dark bar

Mean terminal half-life in healthy men is 17.5 hours. Residual drug is still there at 24 hours. That is chemistry, not a second tablet.

Highlights of the US Cialis label still say the tablet can work up to 36 hours. This page does not add a second program's head-counts to that sentence.

02How many men sat in that timed program?

Four hundred eighty-three men sat in the timed program. They were evenly randomized to placebo, 10 mg, or 20 mg and told which clock to use. This page stays on the 24-hour clock.

Four attempts at the assigned hour were encouraged. Missing one try does not rewrite the mean.

03What were the 24-hour percentages?

At the 24-hour timepoint, mean per-patient successful intercourse attempts were 42% on placebo, 56% on Cialis 10 mg, and 67% on 20 mg. Those are shares of attempts, not a promise that every Sunday works.

This site's starting tablet is 10 mg as needed. The 67% row is the 20 mg arm in that same program.

04What did the 10 mg arm do at 24 hours?

Fifty-six percent on 10 mg is the 24-hour figure next to 42% on placebo. That is the arm that matches this vault's as-needed start.

If Friday 10 mg is the swallow, Saturday evening can still sit on that clock. A second 10 mg the same calendar day is a second dose. Usual frequency is one as-needed tablet a day.

05Why four attempts at the assigned hour?

Four separate attempts at the assigned dose and the 24-hour timepoint were the ask. The percentage is per patient across those tries, not a single lucky night.

Arousal still had to be there on each try. The tablet does not lock an erection for a full day. See stimulation still required.

06Does a working 24-hour tail allow a second swallow?

A working tail is not a second swallow. Most men stay at one as-needed dose per day. Kidney and CYP rows use longer spacing. See one tablet in 24 hours.

Duration questions that are not this 24-hour clock live on the weekend glow pulse.

Sources

  1. DailyMed CIALIS (tadalafil) Clinical Studies, 483-patient timed intercourse program at 24 hours (42 / 56 / 67%)
  2. Young JM et al., J Androl 2005 (483-man timed US trial)

Checked against the current label and reviewed by Dr. Mateo Ruiz. See Probe, Assay, Glow-check, Seal.

Vault consult

Answers follow the U.S. Cialis label.

Ramon C. Is 67% the 10 mg number at 24 hours?

Vault reply

Sixty-seven percent was the 20 mg arm. The 10 mg arm was 56% against 42% on placebo. This vault starts at 10 mg as needed.

Ingrid S. Can I use the Highlights 36-hour line as a second set of head-counts?

Vault reply

Highlights say up to 36 hours. This page does not add another program's n/N to that line. The 483-man clock here is the 24-hour read.

Yusuf M. If Saturday still works, do I take another 10 mg?

Vault reply

No. One as-needed tablet a day is the usual frequency. The 24-hour read is leftover exposure, not a new dose.

Before you start, stop, or change any medicine, speak with your prescriber or pharmacist - they hold your chart, this vault card does not. Open the vault disclaimer.